| 摘要 |
The present invention pertains to compounds of the following formula: (1) wherein: R<ALK >is primary or secondary aliphatic saturated C2-6alkyl; each of R<B2>, R<B3>, R<B4>, and R<B5 >is independently -H, -OH, or -OMe; each of R<1 >and R<2 >is independently: -H, optionally substituted C1-4alkyl, or optionally substituted C5-20aryl; R<A3 >is -H, -OH, -OC(=O)RE, -OS(=O)2OH, or -OP(=O)(OH)2; R<E >is: -H, optionally substituted C1-6alkyl, optionally substituted C3-20heterocyclyl, or optionally substituted C5-20aryl; or a pharmaceutically acceptable salt, solvate, amide, ester, ether, chemically protected form, or prodrug thereof. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, for both diagnosis and treatment of, for example, proliferative conditions, such as cancer, and inflammatory conditions.
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