Novel methods of diagnosing and screening for modulators of tissue remodeling and treating related diseases

摘要

Described herein are methods that can be used for diagnosis of tissue remodeling, as well as tissue remodeling phenotypes. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate tissue remodeling. Additionally, molecular targets (genes and their products) for therapeutic intervention in disorders associated with tissue remodeling are described. Moreover, methods for using such molecular targets are described.