发明名称 |
Isolation, purification and synthesis of procyanidin B2 and uses thereof |
摘要 |
Methods for the synthesis, isolation, and purification of procyanidin B2 are disclosed. The synthetic methods utilize epicatechin as a starting material and produce procyanidin B2 in high yields. The isolation methods extract procyanidin B2 from a sample of bark powder from plant matter of the genus Uncaria. The isolated and/or synthesized procyanidin B2 is used to treat amyloid disease, such as Alzheimer's disease and Parkinson's disease. Pharmaceutical compositions containing the synthesized and/or isolated procyanidin B2 are also disclosed.
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申请公布号 |
US2004260076(A1) |
申请公布日期 |
2004.12.23 |
申请号 |
US20030684178 |
申请日期 |
2003.10.10 |
申请人 |
CASTILLO GERARDO M.;NGUYEN BETH P.;CHOI PAULA Y.;LARSEN LESLEY;LORIMER STEPHEN D.;SNOW ALAN D. |
发明人 |
CASTILLO GERARDO M.;NGUYEN BETH P.;CHOI PAULA Y.;LARSEN LESLEY;LORIMER STEPHEN D.;SNOW ALAN D. |
分类号 |
A61P25/16;A61P25/28;C07D311/62;C07D311/74;C07D407/04;(IPC1-7):C07D311/74 |
主分类号 |
A61P25/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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