| 发明名称 |
FUSED COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR |
| 摘要 |
The present invention discloses novel compounds of general formula (I), or a pharmaceutically acceptable salt or prodrug thereof (in which X1 - X5, R5 -R8b, Z1 - Z2 and Ar1 are defined herein), a method for inhibiting the VR1 receptor in mammals using these compounds, a method for controlling pain in mammals, and pharmaceutical compositions including those compounds and a process for making those compounds.
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| 申请公布号 |
CA2756058(A1) |
申请公布日期 |
2004.12.23 |
| 申请号 |
CA20042756058 |
申请日期 |
2004.06.10 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
GOMTSYAN, ARTHUR;BAYBURT, EROL K.;LEE, CHIH-HUNG;KOENIG, JOHN R.;SCHMIDT, ROBERT;LUKIN, KIRILL;CHAMBOURNIER, GILLES;HSU, MARGARET;LEANNA, ROBERT M.;CINK, RUSSELL D. |
| 分类号 |
C07D403/12;A61K31/416;A61P13/10;A61P29/00;C07C209/24;C07C211/42;C07D217/02;C07D231/56;C07D401/12;C07D401/14 |
主分类号 |
C07D403/12 |
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