发明名称 |
PHENOTHIAZINE ENANTIOMERS AS AGENTS FOR THE PREVENTION OF BONE LOSS |
摘要 |
<p>Disclosed is the unexpected finding that enantiomers of phenothiazines, preferably the (+) enantiomer of promethazine, are particularly effective in inhibiting the bone resorbing cells, osteoclasts, thus providing new uses and methods for reducing bone loss and, e.g., treating periodontitis and osteoporosis. The invention provides a range of such uses, methods, medicaments and associated compositions and kits.</p> |
申请公布号 |
WO2004110458(A1) |
申请公布日期 |
2004.12.23 |
申请号 |
WO2004US15416 |
申请日期 |
2004.05.17 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;SOUTHWEST RESEARCH INSTITUTE;BOLAND, EDWARD, J.;MCDONOUGH, JOE |
发明人 |
BOLAND, EDWARD, J.;MCDONOUGH, JOE |
分类号 |
A61K31/5415;A61P19/10;(IPC1-7):A61K31/541 |
主分类号 |
A61K31/5415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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