发明名称 |
DRUG CONJUGATE COMPOSITION |
摘要 |
The invention provides a liquid composition and a Iyophilized composition comprising a therapeutically effective amount of a conjugate comprising an antibody chemically coupled to a maytansinoid. The invention further provide s a method for killing a cell in a human comprising administering to the human either of the compositions such that the antibody binds to the surface of th e cell and the cytotoxicity of the maytansinoid is activated, whereby the cell is killed. |
申请公布号 |
CA2525553(A1) |
申请公布日期 |
2004.12.23 |
申请号 |
CA20042525553 |
申请日期 |
2004.05.14 |
申请人 |
IMMUNOGEN, INC. |
发明人 |
CHIH, HUNG-WEI;FLEMING, MICHAEL;ZHANG, WEI;AMPHLETT, GODFREY |
分类号 |
A61K47/48 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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