Method of making stem cells from differentiated cells

摘要

Disclosed are methods of creating a stem cell. Specifically described are methods of creating a pluripotent stem cell by reprogramming a differentiated cell. The method of creating the stem cell comprises the steps of obtaining a cytoplast from an existing embryonic stem cell; fusing the cytoplast with a differentiated cell to produce a cybrid; and culturing the cybrid to yield a pluipotent stem cell.