发明名称 |
ROOM TEMPERATURE STORAGE OF ORGANS |
摘要 |
The present invention relates generally to compositions and method for freezing and/or drying organs for storage prior to use. In particular, the present invention relates to the genetic modification of cells used to form organs so that organs formed from the genetically modified cells can be drie d. According to the invention, mammalian cells may be modified with genes encoding plant late embryogenesis protein HVAI, trehalose transport protein, or a trehalose synthesis pathway. The invention also provides methods of treating patients with organs that have been preserved by freezing and/or drying.
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申请公布号 |
CA2527822(A1) |
申请公布日期 |
2004.12.23 |
申请号 |
CA20042527822 |
申请日期 |
2004.05.28 |
申请人 |
STRATATECH CORPORATION |
发明人 |
ALLEN-HOFFMANN, LYNN;CONRAD, PAUL;HOFFMANN, MICHAEL |
分类号 |
C12N5/00;A01N1/02;A61K;A61K35/12;A61K48/00;C07K14/395;C12N5/071;C12N5/10 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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