| 发明名称 |
INHIBITORS OF CELL MIGRATION |
| 摘要 |
The present invention concerns peptide compounds, which were found to bind to the alpha<M#191 integrin I-domain and inhibit its complex formation with proMMP-9, thereby preventing neutrophil migration. The compounds comprise the hexapeptide motif HFDDDE. The compounds can be used in prophylaxis and treatment of inflammatory conditions. |
| 申请公布号 |
WO2004110478(A1) |
申请公布日期 |
2004.12.23 |
| 申请号 |
WO2004FI00376 |
申请日期 |
2004.06.21 |
| 申请人 |
CTT CANCER TARGETING TECHNOLOGIES OY;STEFANIDAKIS, MICHAEL;KOIVUNEN, ERKKI |
发明人 |
STEFANIDAKIS, MICHAEL;KOIVUNEN, ERKKI |
| 分类号 |
A61K38/07;A61P29/00;A61P35/02;C07K14/47;C07K14/705;C12N9/64 |
主分类号 |
A61K38/07 |
| 代理机构 |
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代理人 |
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| 主权项 |
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