BODY WITH A CULTURE SURFACE FOR IN-VITRO PROPAGATION OF CELLS

摘要

Cells (11) that have to be cultured while adhered to a culture surface (2) are cultured on a culture surface (2) in order to propagate them without passaging or with a relevantly reduced number of passaging steps. The culture surface has openings (10) and can be enlarged by stretching. The openings (10) are arranged and configured in such a manner that, in an essentially non-stretched state (a) of the culture surface, are too close (e.g. less than 5ñm) for promoting a population of cells and, in a first stretched state (b) of the culture surface (10'), they are widened (e.g. greater than 10 ñm) whereby enabling them to be populated by cells. The widening of the openings (10) enlarges the culture surface (2) and the cells (11) can continue to propagate without passaging.