发明名称 |
TRANSNASAL MICROEMULSIONS CONTAINING DIAZEPAM |
摘要 |
<p>Diazepam is administered intranasally in the form of specific microemulsions having advantageous properties. The microemulsions are comprised of about equal quantities of a fatty acid and water with the remainder being a hydrophilic surfactant, a polar solvent and an alcohol in a weight ratio such that alcohol is present in a greater quantity by weight than either of the other two. Nasal administration of the subject microemulsions produces a high plasma concentration of diazepam nearly as fast as intravenous administration. The present microemulsions are particularly suitable for a prompt and timely treatment of patients in the acute and/or emergency treatment of status epilepticus and other fever-induced seizures.</p> |
申请公布号 |
WO2004110403(A1) |
申请公布日期 |
2004.12.23 |
申请号 |
WO2004KR01424 |
申请日期 |
2004.06.15 |
申请人 |
SK CORPORATION;CHOI, YONG-MOON;KIM, KWON-HO |
发明人 |
CHOI, YONG-MOON;KIM, KWON-HO |
分类号 |
A61K9/00;A61K9/107;A61K9/14;A61K9/70;A61K47/10;A61K47/14;A61K47/26;(IPC1-7):A61K9/107 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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