| 摘要 |
The present invention is directed to novel biocatalytic processes for the conversion of aliphatic cc, w-dinitriles into the corresponding co- nitrilecarboxylic acid. More particularly, the present invention provides a method for the conversion of 1-cyanocyclohexaneacetonitrile to 1- cyanocyclohexaneacetic acid using an enzyme catalyst with nitrilase activity . 1~cyanocyclohexaneacetic acid is a useful intermediate in the synthesis of gabapentin.
|
