发明名称 NOVEL BRANCHED SIALO-SUGAR MOLECULES AND ANTIVIRAL AGENTS USING THE SAME
摘要 <p>A novel branched sialo-sugar molecule represented by the following formula (I) which is a substance which responds to a variation in the host range of an influenza virus or a variation in antigenicity and is useful as a drug or an adsorbent in a virus removal filter or the like capable of preventing the infection with a type A influenza virus and a type B influenza virus originating in any animals including humans: &lt;CHEM&gt; (wherein NeuAc represents N-acetylneuraminic acid in which the hydroxyl group, the carboxyl group and the amido group may be chemically modified with a halogen group, an alkyl group or an acyl group, either the same group or separate groups, Hex represents hexose, HexNAc represents N-acetylhexosamine and R represents a substrate selected from among a hydrogen atom, a hydrocarbon chain, a sugar chain, a lipid, a protein and a synthetic polymer, R may have a substituent, and the linkage between N-acetylneuraminic acid and hexose may be either an O-glycoside linkage occurring in nature or a chemically converted linkage such as an S-glycoside or a Se-glycoside linkage) is provided.</p>
申请公布号 EP1489101(A1) 申请公布日期 2004.12.22
申请号 EP20030743526 申请日期 2003.02.28
申请人 JAPAN SCIENCE AND TECHNOLOGY AGENCY 发明人 SUZUKI, YASUO;JWA, ILPAL
分类号 A61P31/16;A61K31/715;C07H3/06;(IPC1-7):C08B37/00 主分类号 A61P31/16
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