| 摘要 |
NEW MATERIAL:A compound expressed by formula I [a is 0 or 1; b is 0, 1 or 2; when a and b are 0, c is 4, n is 1 or 2 and m is 0; when a is 1 and b is 0, c is 2, n is 1 or 2 and m is 0 or 1; when b is 1 or 2, c, n and m are 0; R is 4-10C alkoxy or cycloalkyloxy which is substituted by halogen respectively, etc., when b is 2 or formula II or formula III (R0 is 2-6C alkyl) when b is 1; X is halogen; A is caffeine, theophylline, N-methylimidazole, etc.; Y is H2O or R8-OH (R8 is benzyl or alkyl which may be each substituted by lower alkoxy)]. EXAMPLE:An oxychloroeslenium-N-methylimidazole (1:2) complex. USE:An antitumor agent having antitumor activity and antimutagenicity. PREPARATION:A compound expressed by formula IV (when a is 0, c' is 4 and d is 0; when a is 1, c' is 2 and d is 0 or 1) is reacted with a compound expressed by formula F (F is A, etc.) to provide a compound expressed by formula I.
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