发明名称 Orally administered dosage forms of GABA analog prodrugs having reduced toxicity
摘要 The present invention provides an extended release oral dosage form of prodrugs of gabapentin and other GABA analogs, which dosage forms exhibit reduced toxicity. The dosage forms are particularly useful in administering those prodrugs of gabapentin and other GABA analogs that are metabolized to form an aldehyde. The dosage forms of the invention are useful for treating or preventing diseases and/or disorders for which the parent gabapentin or other GABA analog are known to be therapeutically effective.
申请公布号 US6833140(B2) 申请公布日期 2004.12.21
申请号 US20020170127 申请日期 2002.06.11
申请人 XENOPORT, INC. 发明人 CUNDY KENNETH C.;GALLOP MARK A.
分类号 A61K9/22;A61K9/26;A61K31/19;A61K31/197;A61K31/22;A61K31/27;A61K31/341;A61K45/00;A61K47/48;A61P1/00;A61P1/06;A61P19/02;A61P25/00;A61P25/04;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P39/02;A61P43/00;C07C205/43;C07C271/22;C07C323/58;C07D213/80;C07D267/06;C07D307/58;C07D317/22;C07D317/32;C07D317/40;(IPC1-7):A61K9/20;A01N37/02;A01N37/10 主分类号 A61K9/22
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