PROCEDE POUR LA PREPARATION DE COMPOSE PHARMACEUTIQUE ET POUR COMPOSITION PHARMACEUTIQUE LE CONTENANT, ET PROCEDE POUR SA PRODUCTION ET SON UTILISATION DANS LE TRAITEMENT DES MALADIES HYPERPROLIFERATIVES POUR LA PEAU

摘要

The invention relates to a compound of the formula wherein R is hydroxy and R<1> is H2 or CH2, or R is hydrogen or fluoro and R<1> is CH2. Compounds of formula I are useful as agents for the treatment of hyperproliferative skin diseases, such as psoriasis, neoplastic diseases, such as leukemia, and sebaceous gland diseases, such as acne and sebhorreic dermatitis.