发明名称 |
Novel cyano-substituted dihydropyrimidine compounds and their use to treat diseases. |
摘要 |
The present invention provides compounds of formula Iand pharmaceutically acceptable salts thereof.The formula I compounds induce mitotic arrest thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases which can be treated by inducing mitotic arrest. |
申请公布号 |
ZA200307320(B) |
申请公布日期 |
2004.12.20 |
申请号 |
ZA20030007320 |
申请日期 |
2003.09.18 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
SPENCER DAVID KIMBALL;DAVID B. RAWLINS;ROBERT JOSEPH SCHMIDT;LOUIS J. LOMBARDO;HAI-YUN XIAO;DAVID KENT WILLIAMS |
分类号 |
C07D239/36;A61K31/505;A61K31/506;A61K31/513;A61P9/14;A61P35/00;C07D211/90;C07D239/22;C07D239/40;C07D239/42;C07D401/04;C07D401/10;C07D403/10;C07D403/12;C07D405/04;C07D409/04;C07D409/06;C07D409/10;C07D413/04;C07D413/10;C07D413/14;C07D417/04 |
主分类号 |
C07D239/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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