发明名称 |
PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED-3-QUINOLINE AND 3-QUINOL-4- ONE CARBONITRILES |
摘要 |
There is provided a process for the preparation of 7-substituted-3-quinolinecarbonitriles and intermediates useful in a process to prepare 7-substituted-3-quinolinecarbonitriles and pharmaceutically acceptable salts is described. Where 7-fluoro-4-oxo-1,4-dihydro-3-quinolinecarbonitrile is converted in three steps to 7-substituted-3-quinolinecarbonitriles which inhibit the action of certain protein kinases and are useful in the treatment of cancer.
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申请公布号 |
KR20040106420(A) |
申请公布日期 |
2004.12.17 |
申请号 |
KR20047017459 |
申请日期 |
2003.04.29 |
申请人 |
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发明人 |
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分类号 |
C07D215/54;A61K31/4704;A61K31/4709;A61K31/554;A61P35/00;A61P43/00;C07D215/38;C07D215/56;C07D401/12;C07D401/14;C07D405/12;C07D409/12 |
主分类号 |
C07D215/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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