发明名称 |
MULTIDRUG MULTILIGAND CONJUGATES FOR TARGETED DRUG DELIVERY |
摘要 |
Described is a multi drug multiligand conjugate for targeted drug delivery. The MDML conjugate contains a plurality of tripartite molecules linked to a central scaffold moiety, with each tripartite molecule comprising a targeting molecule, a therapeutic agent and a scaffold binding element. The MDML conjugate allows for more efficient delivery of therapeutic agents to the cells resulting in enhanced therapeutic efficiency. A model MDL conjugate is disclosed as well as method for the synthesis of the model conjugate.
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申请公布号 |
WO03035011(A8) |
申请公布日期 |
2004.12.16 |
申请号 |
WO2002US34548 |
申请日期 |
2002.10.28 |
申请人 |
THE UAB RESEARCH FOUNDATION |
发明人 |
SAFAVY, AHMAD |
分类号 |
A61K47/48;A61K51/08;(IPC1-7):A61K51/00;A61K49/00;A61K38/00;A61M36/14;C07K14/00;C07K16/00;C07K17/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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