| 发明名称 |
Substrates and assays for beta-secretase |
| 摘要 |
The present invention is directed to novel substrates for Hu-Asp. More particularly, the invention provides peptide substrates and fusion polypeptide substrates comprising a beta-secretase cleavage site. Methods and compositions for making and using the peptides are disclosed.
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| 申请公布号 |
US2004253706(A1) |
申请公布日期 |
2004.12.16 |
| 申请号 |
US20040801938 |
申请日期 |
2004.03.16 |
| 申请人 |
PHARMACIA & UPJOHN COMPANY, A DELAWARE CORPORATION |
发明人 |
YAN RIQIANG;TOMASSELLI ALFREDO G.;GURNEY MARK E.;EMMONS THOMAS L.;BIENKOWSKI MICHAEL JEROME;HEINRIKSON ROBERT L. |
| 分类号 |
G01N33/50;A61K45/00;A61P25/28;A61P43/00;C07K2/00;C07K5/00;C07K5/103;C07K7/06;C07K7/08;C07K14/47;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12Q1/02;C12Q1/37;G01N33/15;(IPC1-7):C12N9/64 |
主分类号 |
G01N33/50 |
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