发明名称 PYRIDAZINIL QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF TUMOURS
摘要 <p>The invention concerns quinazoline derivatives of Formula (I) wherein Z is an O, S, SO, SO2, N(R&lt;2&gt;) or C(R&lt;2&gt;)(R&lt;3&gt;) group wherein each R&lt;2&gt; or R&lt;3&gt; group is hydrogen or (1-8C)alkyl, m is 1, 2 or 3, each R&lt;1&gt; group has any of the meanings defined in the description, R&lt;a&gt; is halogeno or (1-6C)alkoxy, R&lt;b&gt; is halogeno or (1-6C)alkoxy, and R&lt;c&gt; is hydrogen, halogeno, (1-8C)alkyl or (1-6C)alkoxy, or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-invasive agent in the containment and/or treatment of solid tumour disease.</p>
申请公布号 WO2004108707(A1) 申请公布日期 2004.12.16
申请号 WO2004GB02365 申请日期 2004.06.03
申请人 ASTRAZENECA AB;ASTRAZENECA UK LIMITED;BARLAAM, BERNARD 发明人 BARLAAM, BERNARD
分类号 A61P35/00;C07D403/12;(IPC1-7):C07D403/12;A61K31/517 主分类号 A61P35/00
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