| 摘要 |
The invention relates to an imaging method for simultaneously determining in vivo distributions of bioluminescent and/or fluorescent markers and radioactive markers at identical projection angles. The distribution of the bioluminescent and/or fluorescent markers is determined by means of at least one first detector separately detecting photons which have a first average energy and are emitted by the bioluminescent and/or fluorescent markers while the distribution of the radioactive markers is determined by means of at least one second detector simultaneously but separately detecting photons which have a second average energy and are emitted by the radioactive markers. The invention also relates to a device for carrying out the inventive imaging method, comprising at least one CCD camera (1, 2) as a first detector, at least one single photon emission computed tomographic (SPECT) detector (3) as a second detector, and a layer (5) which essentially reflects the photons of the bioluminescent and/or fluorescent markers and substantially transmits the photons of the radioactive markers. |
