发明名称 |
2-[2-(4-MORPHOLINO)ETHYLAMINO]PYRIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME |
摘要 |
<p>The present invention relates to 2-[2-(4-morpholino)ethylamino]pyridine derivatives useful as an antiviral agent, and more particularly novel 2-[2-(4-morpholino)ethylamino]pyridine derivatives having an excellent inhibitory effect on replication of Hepatitis C virus (HCV), represented by the following formula (I) in which R1 and R2 represent respectively C1-C4 straight or branched alkyl group, C1-C4 straight or branched alkoxy group, methylthio group, trifluoromethyl group, halogen atom, or hydrogen atom, and X represents oxygen atom or sulfur atom; and pharmaceutically acceptable salts thereof, a preparation method thereof, and an antiviral pharmaceutical composition comprising the compound as an effective component. The 2-[2-(4-morpholino)ethylamino]pyridine derivatives according to the present invention have an excellent inhibitory effect on replication of Hepatitis C virus (HCV) and thus can be advantageously used as a therapeutic or prophylactic agent of hepatitis C.</p> |
申请公布号 |
WO2004108719(A1) |
申请公布日期 |
2004.12.16 |
申请号 |
WO2004KR01298 |
申请日期 |
2004.06.01 |
申请人 |
B & C BIOPHARM CO., LTD.;KIM, JONG-WOO;LEE, SANG-WOOK;LEE, GEUN-HYUNG;HAN, JAE-JIN;PARK, SANG-JIN;PARK, EUL-YONG;SHIN, JOONG-CHUL |
发明人 |
KIM, JONG-WOO;LEE, SANG-WOOK;LEE, GEUN-HYUNG;HAN, JAE-JIN;PARK, SANG-JIN;PARK, EUL-YONG;SHIN, JOONG-CHUL |
分类号 |
C07D413/14;C07D213/74;(IPC1-7):C07D413/14 |
主分类号 |
C07D413/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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