发明名称 |
DERACEMISATION OF AMINES |
摘要 |
The present invention relates to a method for the deracemisation or chiral inversion of chiral amines by enzymatic treatment. The method employs a stereoselective enzymatic conversion and either a non-selective or partially selective chemical or enzymatic conversion, simultaneously or sequentially. The invention also provides a method for selecting a suitable enzyme, particularly a suitable amine oxidase, and for the generation of novel enzymes suitable for use in the deracemisation method. |
申请公布号 |
EP1485496(A2) |
申请公布日期 |
2004.12.15 |
申请号 |
EP20030712387 |
申请日期 |
2003.03.19 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
ALEXEEVA, MARINA VICTOROVNA;ENRIGHT, ALEXIS;TURNER, NICHOLAS JOHN;MAHMOUDIAN, MAHMOUD |
分类号 |
C12N15/09;C07B53/00;C07C209/44;C07C211/27;C12N9/06;C12N15/01;C12N15/53;C12P41/00;C12R1/685 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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