发明名称 |
Method for producing organic compounds by substituting halogen atoms |
摘要 |
The invention pertains to a method in which a halogen atom of an organic compound is replaced with a group derived from a nucleophilic agent, at high yield and high efficiency, by the following method which includes a step of reacting the nucleophilic agent with an organic material having a halogen atom bonded to a carbon atom having four sigma bonds, more specifically: a method for producing an organic compound having Q, the method including a step of reacting a compound represented by general formula (2) with an organic starting material having at least one halogen atom bonded to a carbon atom having four sigma bonds so as to replace the halogen atom in the organic starting material with Q: MQa (wherein M represents an alkali metal atom, an alkali earth metal atom, or a rare earth metal atom; Q represents a moiety of an inorganic acid or an active hydrogen compound derived by eliminating a proton, wherein Q is a halogen atom different from the halogen atom in the organic starting material having the halogen atom bonded to the carbon atom having the four sigma bonds; and a represents an integer of 1 to 3) in the presence of a compound represented by general formula (1) <CHEM> (wherein Z<-> represents an anion derived by eliminating a proton from an inorganic acid or an active hydrogen compound; R2 is the same or different; R2 each independently represent a C1-C10 hydrocarbon group or two R2 on the same nitrogen atom may be bonded with each other to form a ring with the nitrogen atom). |
申请公布号 |
EP1486479(A1) |
申请公布日期 |
2004.12.15 |
申请号 |
EP20040253380 |
申请日期 |
2004.06.07 |
申请人 |
MITSUI CHEMICALS, INC. |
发明人 |
FUNAKI, SETSUKO;TANIGUCHI, YOSHITERU;NOBORI, TADAHITO;YAMAMOTO, YOSHIHIRO;HARA, ISAO;HAYASHI, TAKAOMI;MIZUTANI, KAZUMI;KIYONO, SHINJI |
分类号 |
C07B35/06;C07B37/04;C07B41/00;C07B43/00;C07C17/20;C07C29/124;C07C67/10;C07C67/287;C07C211/42;C07C253/14;C07C253/30;C07C255/03;C07C255/12;C07C255/13;C07C255/19;C07C255/20;C07C255/41;C07C255/46;C07C323/56;C07C331/14;C07D307/14;C07D307/24;C07D307/33 |
主分类号 |
C07B35/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|