发明名称 CONJUGATE BETWEEN MODIFIED SUPERANTIGENE AND COMPOUND DIRECTED TO THE TARGET
摘要 The invention refers to a conjugate which consists of covalently linked between each other biospecific ligand which can bind with predefined structure of cell surface and mutated superantigene which have decreased affinity to antigenes MNS class II. Conjugate have an ability to activate the T-lymphocites for lysis of cells which express noted cell surface structure that is associated with disease such as malignant tumor, viral infection, autoimmune diseases.
申请公布号 UA73067(C2) 申请公布日期 2004.12.15
申请号 UA19970020534 申请日期 1995.06.07
申请人 ACTIVE BIOTECH AB 发明人
分类号 C12N15/09;A61K38/00;A61K39/00;A61K39/395;A61K47/48;C07K14/31;C07K16/30;C07K16/32;C07K16/46;C07K19/00;C12N15/00;C12N15/01;C12P21/02;C12R1/44;(IPC1-7):C07K16/46 主分类号 C12N15/09
代理机构 代理人
主权项
地址