BENUTZUNG EINES CO2-ABSORBIERERS ZUR STABILISIERUNG EINER ALKALISCHEN TROCKENREAGENZ IM NACHWEIS VON KREATININ

摘要

Disclosed is an improvement to the method for the detection of creatinine in which creatinine, in aqueous solution, is contacted with a dry reagent system of an indicator for creatinine. The assay is carried out at a pH above about 11.5 which is maintained by an alkaline material. The improvement involves packaging the reagent system with a material capable of absorbing CO2 and at least some ambient water vapor. This inhibits the formation of carbonic acid thereby reducing the neutralization of the alkaline reagent system during storage to increase the shelf life and decrease the variability of the system.