| 发明名称 |
MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM |
| 摘要 |
Novel ethylene glycol compounds bearing various functional groups are used t o prepare oligomeric structures. The ethylene glycol monomers can be joined via standard phosphate linkages including phosphoroth ioate, phosphodiester, and phosphoramidate linkages. Uss eful functional groups include nucleobases as well as polar groups, hydrophobic g roups, ionic groups, aromatic groups and/or groups that participate in hydrogen-bonding.
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| 申请公布号 |
CA2180867(C) |
申请公布日期 |
2004.12.14 |
| 申请号 |
CA19952180867 |
申请日期 |
1995.01.11 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
DAVIS, PETER W.;COOK, PHILLIP DAN;ACEVEDO, OSCAR L.;ECKER, DAVID J.;HEBERT, NORMAND |
| 分类号 |
C07D295/08;A61K31/40;A61K31/403;A61K31/404;A61K31/70;A61K31/7088;A61P1/00;A61P1/04;A61P17/00;A61P17/04;A61P29/00;A61P43/00;C07B61/00;C07C31/20;C07C43/13;C07C43/178;C07C237/04;C07C317/16;C07C323/10;C07C325/00;C07C327/20;C07C327/38;C07C333/02;C07D207/325;C07D209/08;C07D233/60;C07D239/24;C07D239/26;C07D239/42;C07D239/54;C07D279/18;C07D471/04;C07D473/18;C07D473/26;C07D473/34;C07F9/08;C07F9/141;C07F9/143;C07F9/22;C07F9/24;C07F9/572;C07F9/59;C07F9/6503;C07F9/6506;C07F9/6509;C07F9/6512;C07F9/6521;C07F9/6533;C07F9/6547;C07F9/6561;C07H21/00;C08G79/02;C08G79/04;C12Q1/68;(IPC1-7):C07H21/00;C07F9/547 |
主分类号 |
C07D295/08 |
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