发明名称 |
INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 - NS4 PROTEASE. |
摘要 |
<p>The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.</p> |
申请公布号 |
MXPA04009938(A) |
申请公布日期 |
2004.12.13 |
申请号 |
MX2004PA09938 |
申请日期 |
2003.04.11 |
申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
MARK A. MURCKO |
分类号 |
C12N9/99;A61K38/00;A61K38/04;A61P1/16;A61P31/12;A61P31/14;A61P37/02;A61P43/00;C07D209/42;C07D401/12;C07D403/12;C07D405/12;C07D405/14;C07D417/12;C07D471/04;C07K5/04;C07K5/06;C07K5/10;C07K7/02;(IPC1-7):A61K31/404;C07F5/02;C07K5/08 |
主分类号 |
C12N9/99 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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