发明名称 |
Novel anti-inflammatory 17.alpha.-heterocyclic-esters of 17.beta.carbothioate androstane derivatives |
摘要 |
There are provided compounds of formula (I) wherein R1 represents C1-6 alkyl or C1-6 haloalkyl; R2 represents a 4-7 membered non-aromatic ring containing 1-3 heteroatoms selected from O, N and S optionally substituted with one or more methyl, ethyl or halogen groups; R3 represents hydrogen, methyl (which may be in either the alpha or beta configuration) or methylene; R4 and R5 are the same or different and each represents hydrogen or halogen; and (a) represents a single or a double bond; and salts and solvates thereof; processes for preparing them and their use in therapy.
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申请公布号 |
US2004248867(A1) |
申请公布日期 |
2004.12.09 |
申请号 |
US20040480071 |
申请日期 |
2004.06.15 |
申请人 |
BIGGADIKE KEITH;JONES PAUL |
发明人 |
BIGGADIKE KEITH;JONES PAUL |
分类号 |
A61K9/12;A61K31/18;A61K31/568;A61K45/00;A61K47/06;A61P5/44;A61P29/00;A61P37/08;A61P43/00;C07J17/00;C07J31/00;C07J33/00;C07J43/00;(IPC1-7):C07J43/00;A61K31/58 |
主分类号 |
A61K9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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