发明名称 |
Detection of clonal T-cell receptor-gamma gene rearrangement by PCR/temporal temperature gradient gel electrophoresis (TTGE) |
摘要 |
The present invention provides methods and compositions for detecting and analyzing clonal T-cell receptor (TCR) gene rearrangement using temporal temperature gradient gel electrophoresis (TTGE), which employs a gradual and uniform increase in the temperature of a constant denaturing gel to resolve different DNA molecules based on base pair composition. The present invention also provides methods and compositions for providing appropriate DNA migration markers for TTGE analysis.
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申请公布号 |
US2004248172(A1) |
申请公布日期 |
2004.12.09 |
申请号 |
US20040824187 |
申请日期 |
2004.04.13 |
申请人 |
QUEST DIAGNOSTICS INVESTMENTS INCORPORATED |
发明人 |
SAMOSZUK MICHAEL;ZHU DAN |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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