| 发明名称 |
Methods for rational pegylation of proteins |
| 摘要 |
The present invention relates to the use of simulation technology to rationally optimize the locations and sizes of attached polymeric moieties for modification of therapeutic proteins and the proteins generated from this method.
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| 申请公布号 |
US2004249576(A1) |
申请公布日期 |
2004.12.09 |
| 申请号 |
US20040820466 |
申请日期 |
2004.03.31 |
| 申请人 |
XENCOR |
发明人 |
DESJARLAIS JOHN RUDOLPH;ZALEVSKY JONATHAN |
| 分类号 |
A61K47/48;C07K1/107;C07K14/505;C07K14/525;C07K14/56;C07K14/61;G01N31/00;G01N33/48;G01N33/50;G06F19/00;(IPC1-7):G06F19/00 |
主分类号 |
A61K47/48 |
| 代理机构 |
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