发明名称 OZONIDES OF TERPENES AND THEIR MEDICAL USES
摘要 Ozonides of terpenes are disclosed. Terpenes which are believed to be pharmacologically active when prepared in accordance with the present invention include: limonene, citronella, alpha-carotene, beta-carotene, Vitamin A, linalool, linalyl acetate, or squalene. Other compounds which are believed to make pharmacologically active terpene ozonides in accordance with the present invention include geraniol, limonene, alpha-pinene, loganin, cymene, farnesanes, eudesmanes, acoranes, cedranes, chamigranes, caryophyllanes, illudanes, humulenes, himachalenes, longifolanes, perhydroazulenes, quaianes, quaianolides, or germacranes. Still other compounds which are believed to make pharmacologically active terpene ozonides in accordance with the present invention include labdanes, clerodanes, abietic acid, phyllocladene, giberellins, ophiobolin A, retigeranic acid, gasgardic acid, lanosterol, euphol, oleanane, ursane, lupeol, hydroxyhopanone, lupanes, or hopanes. Other particular terpene compounds which are believed to make pharmacologically active terpene ozonides when prepared in accordance with the present invention include B-selinene, zingibene, camphene, sabinene, ocimene, myrcene, nerol, citral A, citral B, farnesol, bisabolene, phytol, and cecropia hormone. A method of producing the terpene ozonides is also disclosed. Further, pharmaceutical preparations using these compositions are disclosed. Methods of medical treatment using these pharmaceutical preoarations are also disclosed.
申请公布号 CA1338083(C) 申请公布日期 1996.02.27
申请号 CA19890603585 申请日期 1989.06.22
申请人 HERMAN, STEPHEN 发明人 HERMAN, STEPHEN
分类号 A61K31/08;A61K8/00;A61K31/335;A61K31/357;A61P17/00;A61P29/00;A61P31/04;A61P31/12;A61P35/00;A61Q17/04;C07D323/00;C07D323/02;C07G99/00;(IPC1-7):A61K31/335 主分类号 A61K31/08
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