RECOMBINANT ANTI-LHRH VACCINES

摘要

The present invention relates to oligonucleotide sequences of SEQ ID Nos. 1 and 2, and polypeptide sequences of SEQ ID No. 3 and 4, useful for preparing recombinant anti-LHRH DNA and proteinic vaccines; also, a method of obtaining the vaccines using oligonucleotide sequence of SEQ ID No. 1 or 2; further, the vaccine compositions comprising DNA and/or proteinic vaccines optionally along with an adjuvant and/or delivery system; and lastly, a method of reducing levels of sex steroid hormones by eliciting an effective antibody response against LHRH in mammals of both sexes using the vaccine compositions, for controlling and/or treating the sex-steroid hormone dependent benign prostate hypertrophy and/or prostate cancer, breast cancer, estrus of companion animals, or meat quality of male animals.