发明名称 |
VASCULAR THERAPEUTICS |
摘要 |
The present invention provides a method of preventing or reducing restenosis, neointima formation, graft failure, atherosclerosis, angiogenesis and/or solid tumour growth in a subject. The method comprises administering to the subject a prophylactically effective dose of a nucleic acid which decreases the level of c-Jun mRNA, c-Jun mRNA translation or nuclear accumulation or activity of c-Jun. It is preferred that the nucleic acid is a DNAzyme that targets c-Jun mRNA.
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申请公布号 |
WO03072114(A9) |
申请公布日期 |
2004.12.09 |
申请号 |
WO2003AU00237 |
申请日期 |
2003.02.27 |
申请人 |
UNISEARCH LIMITED;KHACHIGIAN, LEVON, MICHAEL |
发明人 |
KHACHIGIAN, LEVON, MICHAEL |
分类号 |
C12N15/09;A61K31/7088;A61K48/00;A61P9/00;A61P9/10;A61P27/02;A61P35/00;A61P37/06;A61P43/00;C12N9/00;C12N15/113;C12N15/85;C12Q1/68;(IPC1-7):A61K31/708 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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