发明名称 |
Non-irritation non-sensitizing non-ototoxic otic anti-bacterial compositions |
摘要 |
The invention is directed to an aqueous non-ototoxic, topical, otic pharmaceutical composition of matter for treating a mammal consisting essentially of: ciprofloxacin or a pharmaceutically acceptable salt thereof in aqueous solution in an amount effective for antibacterial action; hydrocortisone or a pharmaceutically acceptable salt thereof in an amount effective as an anti-inflammatory agent; polyvinyl alcohol at least about 85% hydrolyzed in an amount effective to suspend the hydrocortisone in solution; water sufficient to produce an aqueous composition; benzyl alcohol in an amount effective for antibacterial action; lecithin in an amount effective for enhancing suspension of other constituents in the composition; and polysorbate ranging from polysorbate 20 to 80 in an amount effective for spreading the preparation on a hydrophobic skin surface to the site of infection or inflammation. |
申请公布号 |
ZA9604653(B) |
申请公布日期 |
1996.12.12 |
申请号 |
ZA19960004653 |
申请日期 |
1996.06.05 |
申请人 |
BAYER CORPORATION. |
发明人 |
SHIVAJI PURWAR;DAVID GOLDMAN |
分类号 |
A61K9/00;A61K9/10;A61K31/57;A61K47/00;A61K47/32;A61P27/16 |
主分类号 |
A61K9/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|