| 发明名称 |
NOVEL G PROTEIN-COUPLED RECEPTOR UP-REGULATED IN PROSTATE CANCER AND USES THEREOF |
| 摘要 |
A novel gene (designated PHOR-1) that is highly over-expressed in prostate and other cancers and its encoded protein are described. PHOR-1 is a G protein-coupled receptor with homology to receptors involved in olfaction. PHOR-1 in normal human tissues is restricted to prostate, and this gene is highly over-expressed in prostate cancer as well as in cancers of the kidney, uterus, cervix, stomach and rectum. Consequently, PHOR-1 provides a diagnostic and/or therapeutic target for prostate cancer.
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| 申请公布号 |
US2004248088(A1) |
申请公布日期 |
2004.12.09 |
| 申请号 |
US20010017066 |
申请日期 |
2001.12.14 |
| 申请人 |
RAITANO ARTHUR B.;AFAR DANIEL E.H.;JAKOBOVITS AYA;FARIS MARY;HUBERT RENE S.;MITCHELL STEVE CHAPPELL;SAFFRAN DOUGLAS C. |
发明人 |
RAITANO ARTHUR B.;AFAR DANIEL E.H.;JAKOBOVITS AYA;FARIS MARY;HUBERT RENE S.;MITCHELL STEVE CHAPPELL;SAFFRAN DOUGLAS C. |
| 分类号 |
A61K38/00;A61K39/00;A61P13/08;C07K14/705;C12N15/12;(IPC1-7):C12Q1/68;G01N33/574;C07H21/04;C12N9/16 |
主分类号 |
A61K38/00 |
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