发明名称 |
Assay for identifying biological targets of polynucleotide-binding compounds |
摘要 |
The present invention provides methods and systems for the identification of a biological target of a chemical compound, such as saframycin A, known to bind a polynucleotide. The invention also provides methods of screening chemical compounds for those which act in a similar method and may be more potent than known compounds. The inventive methods are particularly useful in the high-throughput screening of chemical compounds that target GAPDH. The invention also provides kits useful in the practice of the inventive method. Compounds identified by inventive methods are also included in the invention.
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申请公布号 |
US2004248100(A1) |
申请公布日期 |
2004.12.09 |
申请号 |
US20030453243 |
申请日期 |
2003.06.03 |
申请人 |
MYERS ANDREW G.;LAPORTE JACOB R.;XING CHENGGUO |
发明人 |
MYERS ANDREW G.;LAPORTE JACOB R.;XING CHENGGUO |
分类号 |
C12M1/34;C12Q1/32;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C12M1/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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