摘要 |
The present invention provides <CHEM> wherein X is alpha -CH2OR<1> when A is alpha -hydro, A and B together are ethylene, and C and D together are ethylene, beta -CH2OR<1>, or -CO-; R is -H or n-butylsulfonoyl; R<1> is R provided that at least one of R and R<1> must be n-butylsulfonoyl; R<2> is -H, alpha - or beta -hydroxy, or alpha - or beta -n-butylsulfonoyl; A is <CHEM> B is <CHEM> C is -CH2 or <CHEM> and D is -CH2 or <CHEM> methods of inhibiting estrogen deficient patholigies, and pharmaceutical formulations. |