| 发明名称 |
PROCESS FOR THE PURIFICATION OF (25,35)-2,3-DIHYDRO-3- HYDROXY-2-(4-METHOXY-PHENYL)-1, 5-BENZOTHIAZEPIN-4(5H)-ONE |
| 摘要 |
A purification method of intermediates for preparation of Diltiazem which consists of the crystallization of mixture enantiomerically enriched in (2S,3S)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)--1,5-benzothiazepin-4(5H)- one is described.
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| 申请公布号 |
CA2020158(C) |
申请公布日期 |
1997.03.04 |
| 申请号 |
CA19902020158 |
申请日期 |
1990.06.29 |
| 申请人 |
ZAMBON GROUP S.P.A. |
发明人 |
GIORDANO, CLAUDIO;TENTORIO, DARIO;RUSSO, LAURA |
| 分类号 |
C07B57/00;C07D281/10;(IPC1-7):C07D281/10 |
主分类号 |
C07B57/00 |
| 代理机构 |
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