发明名称 Enhanced gene expression using vectors
摘要 There is described a vector able to express a transgene under the control of a promoter, the duration of expression being enhanced by the exposure of the vector to cytomegalovirus pp71 or a homologue thereof. Usually the vector will be a viral vector and Herpesvirus vectors are preferred. Suitable cytomegalovirus pp71 proteins include, but are not limited to, mouse, rat, chimpanzee, simian, equine and guinea pig pp71 proteins, but human pp71 is preferred. The vector may itself include the gene for expression of cytomegalovirus pp71.
申请公布号 US2004248300(A1) 申请公布日期 2004.12.09
申请号 US20040489744 申请日期 2004.07.27
申请人 PRESTON CHRISTOPHER MAURICE 发明人 PRESTON CHRISTOPHER MAURICE
分类号 A61K48/00;C07K14/045;C12N15/869;(IPC1-7):C12N15/86;C12N7/00 主分类号 A61K48/00
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