发明名称 |
CRYTALS AND STRUCTURES OF C-ABL TYROSINE KINASE DOMAIN |
摘要 |
The present invention provides machine readable media embedded with the three~dimensional molecular structure coordinates of Ab1KD and variants and subsets thereof, including binding pockets, methods of using the structure t o identify and design affecters, including inhibitors and activator Ab1KD crystals and compounds and compositions that affect Abl activity.
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申请公布号 |
CA2525681(A1) |
申请公布日期 |
2004.12.09 |
申请号 |
CA20042525681 |
申请日期 |
2004.05.21 |
申请人 |
SGX PHARMACEUTICALS, INC. |
发明人 |
BUCHANAN, SEAN GRANT;LOUIE, GORDON V.;ARNOLD, WILLIAM D.;CHIE LEON, BARBARA |
分类号 |
C12N9/12;C12Q1/48;C40B30/02;C40B50/02;G01N25/14;G06F17/30;G06F19/00 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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