发明名称 |
Delivery system with increased bioavailability |
摘要 |
<p>The present invention is directed to a dry composition which allows delivery of active agents with good bioavailability. These compositions are prepared by emulsifying the active agent using liposome technology known in the art and then encapsulating with a modified starch. The modified starch is prepared by enzymatic hydrolysis of starch after the preparation of a starch derivative containing a hydrophobic group or both a hydrophobic and a hydrophilic group. The resultant composition is a dry powder with excellent bioavailability. Further, the composition has good load levels and stability.</p> |
申请公布号 |
EP1484055(A1) |
申请公布日期 |
2004.12.08 |
申请号 |
EP20040012901 |
申请日期 |
2004.06.01 |
申请人 |
NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION |
发明人 |
TRUBIANO, PAOLO C.;MAKARIOUS, AFAF G. |
分类号 |
A61K9/127;A61K47/36;A61K9/14;A61K9/16;A61K9/20;A61K9/48;A61K31/122;A61K47/26;A61P3/00;A61P9/00;A61P17/16;A61P35/00;A61P37/02;A61P43/00;(IPC1-7):A61K9/16 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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