发明名称 |
CONJUGATES OF NUCLEOSIDES WITH LACTOSAMINATED HUMAN ALBUMINE |
摘要 |
Pharmaceutical compositions containing as active compound conjugates of lactosaminated albumin with antiblastic nucleosides (and their analogs) are here described. These compositions are particularly useful to increase the efficacy of the antiblastic nucleosides (and their analogs) on liver micrometastases. They preferably consist of aqueous solutions administered by parenteral route, preferably by intravenous injection. The antiblastic nucleoside of choice is 5-fluoro-2'-deoxyuridine (FUdR). |
申请公布号 |
EP1351700(B1) |
申请公布日期 |
2004.12.08 |
申请号 |
EP20020708297 |
申请日期 |
2002.01.07 |
申请人 |
UNIVERSITA' DI BOLOGNA |
发明人 |
FIUME, LUIGI;DI STEFANO, GIUSEPPINA;BUSI, CORRADO |
分类号 |
A61K47/48 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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