发明名称 |
Use of 2-deoxy ecdysterone for the preparation of a medicament for inducing labour or abortion |
摘要 |
The invention provides a process for the isolation of 2-deoxy ecdysterone from Zoanthus sp. process comprising the steps (a) preparing crude methanol extract of Zoanthus sp., (b) subjecting the crude methanol extract to fractionation using petroleum ether, ethyl acetate, chloroform, n-butanol and mixtures thereof to yield a fraction, (c) subjecting the active fraction to flash chromatography over silica gel to obtain partially purified active compound, and (d) subjecting the active subfraction obtained from step (c) above to gel permeation chromatography to obtain the active pure compound. The invention also concerns the use of 2-deoxy ecdysterone for the preparation of a medicament for the induction of labour or the interruption of pregnancy. |
申请公布号 |
EP1240898(A3) |
申请公布日期 |
2004.12.08 |
申请号 |
EP20020013143 |
申请日期 |
2000.03.31 |
申请人 |
COUNCIL OF SCIENTIFIC ANDINDUSTRIAL RESEARCH |
发明人 |
GONSALVES, CYNTHIA;SUBRAYAN, PERUNNINAKULATH PARAMESWARAN;NAIK, CHANDRAKANT GOVIND;ACHUTHANKUTTY, CHITTUR THELAKKAT |
分类号 |
A61K31/575;A61P15/04;C07J9/00 |
主分类号 |
A61K31/575 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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