| 发明名称 |
Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade |
| 摘要 |
The present invention relates to compounds, and prodrugs thereof, composition and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
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| 申请公布号 |
US6828338(B2) |
申请公布日期 |
2004.12.07 |
| 申请号 |
US20030465125 |
申请日期 |
2003.06.19 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
SOUTH MICHAEL J.;CASE BRENDA;GARLAND DANNY J.;HAYES MICHAEL J.;HUANG HORNG-CHIH;HUANG WEI;JONES DARIN E.;NEUMANN WILLIAM L.;PARLOW JOHN J.;REITZ DAVID B.;RUEPPEL MELVIN L.;WEBBER RONDALD K. |
| 分类号 |
A61K31/44;A61K31/4418;A61K31/4436;A61K31/4439;A61K45/00;A61P7/02;A61P9/10;A61P11/00;A61P35/00;A61P43/00;C07D213/74;C07D213/89;C07D401/10;C07D409/04;(IPC1-7):A61K31/44;C07D213/02 |
主分类号 |
A61K31/44 |
| 代理机构 |
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代理人 |
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| 主权项 |
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