发明名称 |
L-ascorbic acid-2-o-maleic acid-a-tocopherol diester 1-propanol adduct and process for producing the same |
摘要 |
L-Ascorbic acid-2-O-maleic acid-alpha-tocopherol diester.1-propanol adduct or its pharmacologically acceptable salt; cosmetic components, antioxidants, radical scavengers, anti-inflammatory agents and elastase inhibitors containing the same as the active ingredient; and a process for producing the above-described adduct characterized by comprising extracting a solution containing L-ascorbic acid-2-O-maleic acid-alpha-tocopherol diester with a solvent, distilling off the solvent, and adding to the residue 1-propanol mixed with an organic solvent followed by crystallization. |
申请公布号 |
US6828348(B2) |
申请公布日期 |
2004.12.07 |
申请号 |
US20030479145 |
申请日期 |
2003.11.25 |
申请人 |
SENJU PHARMACEUTICAL CO., LTD. |
发明人 |
OGATA KAZUMI;SAITO NORIKO;YAMADA KAZUHIKO;MARUYAMA GENTA |
分类号 |
A61K8/49;A61P17/16;A61P29/00;A61P39/06;A61P43/00;C07D407/12;C07H19/23;(IPC1-7):C07D311/72;C07D307/62;A61K7/42;A61K31/355;A61K31/375 |
主分类号 |
A61K8/49 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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