METHOD FOR PREPARING BIODEGRADABLE POROUS SUPPORT FOR TISSUE ENGINEERING WITHOUT ORGANIC SOLVENT

摘要

PURPOSE: Provided is a method for preparing biodegradable porous polymer support for tissue engineering without organic solvent, which is used for regeneration of tissue and excellent in stability. CONSTITUTION: The porous polymer support for tissue engineering is prepared by mixing polymer powder and water soluble salts uniformly; pressing the resulting mixture in mold; jointing the obtained press molding while heating; and removing the water soluble salts from the molding. The polymers are biodegradable polymers selected from the group consisting of polylactide, polyglycolide, polycaprolactone, polytrimethylene carbonate, polyamino acid, polyorthoester, polyethylene oxide and copolymer thereof. The polymers are also nondegradable polymers selected from the group consisting of polyurethane, polyethylene and polycarbonate. The support has the porosity of 50 to 99%. And the pores in the support have the size of 1 to 800 micrometers.