NON-INVASIVE METHODS OF DETECTING ANALYTE CONCENTRATIONS USING HYPEROSM OTIC FLUIDS

摘要

A non-invasive method of determining the concentration of an analyte compris es topographically applying a hyperosmotic solution to an area of the skin. The hyperosmotic solution is adapted to at least partially absorb into the area of the skin such that the skin becomes generally transparent. An optical readhead is placed over the generally transparent area of the skin. The amount of light of the analyte is measured using at least one wavelength via the optical readhead. The concentration of the analyte is calculated fro m the amount of light. The analyte may be glucose and the hyperosmotic solution may be glycerol.