Ligand array assays having reduced fluorescent dye degradation and compositions for practicing the same

摘要

Ligand array assays that exhibit reduced dye degradation and compositions for use in practicing the same are provided. A feature of the subject methods is that they include a label degradation inhibitor deposition step. In this degradation inhibitor deposition step, the surface of a sample exposed array is contacted with a low surface tension fluid, e.g., acetonitrile, that includes a fluorescent dye degradation inhibitor. Also provided are kits for use in practicing the subject methods. The subject methods-and kits find use in a variety of ligand array based applications, including genomic and proteomic applications.